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Translational Pain Research : From Mouse to Man (Frontiers in Neuroscience)

By: Alan R Light (Edited by) , Lawrence Kruger (Edited by)

Out of stock

Ksh 50,650.00

Format: Hardback or Cased Book

ISBN-10: 1439812098

ISBN-13: 9781439812099

Collection / Series: Frontiers in Neuroscience

Collection Type: Publisher collection

Publisher: Taylor & Francis Inc

Imprint: CRC Press Inc

Country of Manufacture: US

Country of Publication: GB

Publication Date: Nov 24th, 2009

Publication Status: Active

Product extent: 456 Pages

Weight: 748.00 grams

Product Classification / Subject(s): Medical research
Pain & pain management

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Bringing together advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, this book examines rodent models for pain associated with bone cancer, osteoarthritis and cardiac episodes.

One of the Most Rapidly Advancing Fields in Modern Neuroscience

The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, Translational Pain Research: From Mouse to Man effectively bridges the gap between basic research and patient care by humanely examining rodent models for pain associated with bone cancer, osteoarthritis, fibromyalgia, and cardiac episodes.

Distinguished Team of International Contributors

In addition to addressing the groundbreaking technical advances in tract tracing, endocannabinoids, cannabis, gene therapy, siRNA gene studies, and the role of glia, cytokines, P2X receptors and ATP, this book also presents cutting-edge information on:

  • Nociceptor sensitization
  • Muscle nociceptors and metabolite detection
  • Visceral afferents in disease
  • Innovative rodent model for bone cancer pain
  • Highly specific receptor cloning
  • Modular molecular mechanisms relevant to painful neuropathies

This sharply focused work also discusses unexpected discoveries derived from brain-imaging studies related to thalamic pain. Translational Pain Research covers the progress made toward bringing laboratory science (much of it at the molecular level) to our understanding of pain phenomena in humans, with the ultimate goal of reducing the suffering that often accompanies pain and its indirect consequences.


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