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The GnRH Neuron and its Control (Wiley-INF Masterclass in Neuroendocrinology Series)

By: Allan E. Herbison (Edited by) , Tony M. Plant (Edited by)

Extended Catalogue

Ksh 32,550.00

Format: Hardback or Cased Book

ISBN-10: 1119233240

ISBN-13: 9781119233244

Collection / Series: Wiley-INF Masterclass in Neuroendocrinology Series

Collection Type: Publisher collection

Publisher: John Wiley and Sons Ltd

Imprint: Wiley-Blackwell

Country of Manufacture: SG

Country of Publication: GB

Publication Date: Apr 27th, 2018

Publication Status: Active

Product extent: 536 Pages

Weight: 1070.00 grams

Dimensions (height x width x thickness): 17.80 x 25.00 x 2.80 cms

Product Classification / Subject(s): Neurosciences
Animal physiology

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The GnRH Neuron and its Control examines the developmental biology of GnRH neurons including their birth in the nasal placode of the early embryo, perinatal programming, and sexual differentiation, in addition to the hypothalamic mechanisms that control GnRH neurons in adulthood to generate pulsatile and surge modes of GnRH secretion throughout the major life stages including aging. The morphology, electrophysiology, signal transduction pathways, transcriptional regulators, and genomics underlying function of the adult GnRH neuron is discussed in detail, as is the neuroendocrinology and cell biology governing the generation of both modes of GnRH release. The book also reviews the neurobiological mechanisms and circuitry responsible for the modulation of the activity of GnRH neurons by season, stress, nutrition, and metabolism, and covers the current and potential therapeutic approaches to regulating GnRH secretion and action. Filled with newly identified research and classical fundamental knowledge to GnRH biology, it will provide students, researchers, and practitioners with an in-depth understanding of reproductive neuroendocrinology. This is the fifth volume in the Masterclass in Neuroendocrinology Series, a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

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