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Review of the Department of Defense Biokinetic Modeling Approach in Support of Establishing an Airborne Lead Exposure Limit

By: (Author) Board on Environmental Studies and Toxicology , (Author) Committee to Review DoD's Proposed Occupational Exposure Limits for Lead , (Author) Division on Earth and Life Studies , (Author) and Medicine National Academies of Sciences Engineering

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Ksh 6,300.00

Format: Paperback or Softback

ISBN-10: 0309671922

ISBN-13: 9780309671927

Publisher: National Academies Press

Imprint: National Academies Press

Country of Manufacture: GB

Country of Publication: GB

Publication Date: Apr 30th, 2020

Print length: 48 Pages

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Biokinetic modeling provides a mathematical technique for estimating absorption, distribution, metabolism, and excretion of chemicals, including particles and metals, in humans. Such models can be used to relate the amount of lead external exposure to the amount of lead found in the blood and other tissues at different points in time. At the request of the Department of Defense (DoD), Review of the Department of Defense Biokinetic Modeling Approach in Support of Establishing an Airborne Lead Exposure Limit evaluates whether the model used by DoD to derive airborne lead concentrations from blood lead levels is appropriate. This report also considers whether DoD's modifications to the model are appropriately justified, and whether the assumptions in and inputs to the model are reasonable. Table of ContentsFront MatterSummary1 Introduction2 Committee's Approach to Its Task3 Committee's Review of the DoD-O'Flaherty ModelReferencesAppendix A: Statement of TaskAppendix B: Committee Member Biosketches

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