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Randomized Clinical Trials of Nonpharmacological Treatments (Chapman & Hall/CRC Biostatistics Series)

By: David Moher (Edited by) , Isabelle Boutron (Edited by) , Philippe Ravaud (Edited by)

Manufacture on Demand

Ksh 12,150.00

Format: Paperback or Softback

ISBN-10: 0367576805

ISBN-13: 9780367576806

Collection / Series: Chapman & Hall/CRC Biostatistics Series

Collection Type: Publisher collection

Publisher: Taylor & Francis Ltd

Imprint: Chapman & Hall/CRC

Country of Manufacture: GB

Country of Publication: GB

Publication Date: Jun 30th, 2020

Publication Status: Active

Product extent: 403 Pages

Weight: 618.00 grams

Dimensions (height x width x thickness): 15.50 x 23.30 x 2.90 cms

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Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable devices, non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions. This book focuses on the methods of assessing nonpharmacological treatments, highlighting specific issues, and discussing trial design

Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable and non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions. Unlike pharmacological treatments, these have no specific requirements for approval. Consequently, they can be widely proposed in clinical practice but may not have been adequately evaluated. This situation is an important barrier for the evaluation of the beneficial effects of these treatments and the conduct of clinical trials. Randomized Clinical Trials of Nonpharmacologic Treatments focuses on the methods for assessing nonpharmacological treatments, highlighting specific issues and trial design.





Features:







  • Chapters written by international experts in the field


  • Highlights specific issues in assessing nonpharmacological treatments in trials including:








    • how to overcome the difficulties of blinding patients, care providers, and outcome assessors


    • the complexity of the intervention, the learning curve, and the clustering effect


    • placebos that can be used


    • issues of assessing harm and assessing the applicability of trials






  • Presents a variety of trial designs for nonpharmacological treatments—including cluster randomized controlled trials, expertise-based trials, pragmatic trials, and nonrandomized trials.


  • Provides several examples of the planning, conduct, analyses, and reporting of trials in different fields, including surgery, technical interventions, medical devices, rehabilitation, psychotherapy, and behavioral interventions.






Providing practical examples that underline these issues and solutions, this book is one of the first to exclusively explore this topic, discussing various categories of treatments, from surgical procedures to psychotherapy.


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