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Molecular Epidemiology : Applications in Cancer and Other Human Diseases

By: Christine B. Ambrosone (Edited by) , Peter G. Shields (Edited by) , Timothy R. Rebbeck (Edited by)

Manufacture on Demand

Ksh 41,800.00

Format: Hardback or Cased Book

ISBN-10: 1420052918

ISBN-13: 9781420052916

Publisher: Taylor & Francis Inc

Imprint: CRC Press Inc

Country of Manufacture: GB

Country of Publication: GB

Publication Date: May 21st, 2008

Publication Status: Active

Product extent: 316 Pages

Weight: 725.00 grams

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Covering design considerations, measurement issues, and methods of statistical inference, and filled with scientific tables, equations, and pictures, Molecular Epidemiology: Applications in Cancer and Other Human Diseases presents a solid, single-source foundation for conducting and interpreting molecular epidemiological studies.

This volume comprises the investigation of factors that may predict the response to treatment, outcome, and survival by exploring:

• design considerations in molecular epidemiology, including:

  • case-only
  • family-based
  • approaches for evaluation of genetic susceptibility to exposure and addiction pharmacogenetics
  • incorporation of biomarkers in clinical trials

• measurement issues in molecular epidemiology, including

  • DNA biosampling methods
  • principles for high-quality genotyping
  • haplotypes
  • biomarkers of exposure and effect
  • exposure assessment

• methods of statistical inference used in molecular epidemiology, including

  • gene-gene and gene-environment interaction analysis
  • novel high-dimensional analysis approaches
  • pathway-based analysis methods
  • haplotype methods, dealing with race and ethnicity
  • risk models
  • a discussion of reporting and interpreting results

• A specific discussion and synopsis of these methods provides concrete examples drawn from primary research in cancer

Covering design considerations, measurement issues, and methods of statistical inference, and filled with scientific tables, equations, and pictures, Molecular Epidemiology: Applications in Cancer and Other Human Diseases presents a solid, single-source foundation for conducting and interpreting molecular epidemiological studies.


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