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Insight on Genotoxicity

By: Bina Gidwani (Author) , Gunjan Kalyani (Author) , Ravindra Kumar Pandey (Author) , Shiv Shankar Shukla (Author)

Manufacture on Demand

Ksh 11,400.00

Format: Paperback or Softback

ISBN-10: 0367557479

ISBN-13: 9780367557478

Publisher: Taylor & Francis Ltd

Imprint: CRC Press

Country of Manufacture: GB

Country of Publication: GB

Publication Date: Oct 8th, 2024

Publication Status: Active

Product extent: 170 Pages

Weight: 303.00 grams

Product Classification / Subject(s): Pharmacology
Pharmacy / dispensing
Biology, life sciences
Toxicology (non-medical)
Pharmaceutical technology

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  • Description

  • Reviews

This book examines the impact of ICH Guidelines on genetic toxicity testing which is a regulatory requirement for drug discovery and development. Genetic toxicity mechanism has also been discussed in detail with a wider perspective.

Genetic toxicology is considered to be an important assessment tool as there is genetic impact of artificial chemicals. Insight on Genotoxicity discusses testing, mechanism, prediction, and bioindicator of genotoxicity taking into consideration recent advances in nano-engineered particles. Corollary of DNA dent is also discussed in detail taking into consideration the impact of ICH guidelines on genotoxicity testing, which is important for drug discovery innovation and development. Perspective review of genotoxicity evaluation in phytopharmaceuticals has been mentioned along with the prevention of genotoxicity in brief viewpoint.

Salient Features

  • Presents methods, standard protocols, and guidelines for genotoxicity testing

  • Examines the impact of ICH Guidelines on genetic toxicity testing which is a regulatory requirement for drug discovery and development

  • Defines appropriate strategies about advances in in vivo genotoxicity testing which have been listed along with progress and prospects

  • Discusses advancement in the high-throughput approaches for genotoxicity testing

    • Details computational prediction of genotoxicity with consideration of mutagenicity, chromosomal damage caused and strategies for computational prediction in drug development

    • Get Insight on Genotoxicity by at the best price and quality guranteed only at Werezi Africa largest book ecommerce store. The book was published by Taylor & Francis Ltd and it has pages. Enjoy Shopping Best Offers & Deals on books Online from Werezi - Receive at your doorstep - Fast Delivery - Secure mode of Payment

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