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By: (Author) Board on Health Promotion and Disease Prevention , (Author) Immunization Safety Review Committee , (Author) Institute of Medicine , (Author) National Academy of Sciences , (Edited by) Donna A. Almario , (Edited by) Kathleen Stratton , (Edited by) Marie C. McCormick , (Edited by) Theresa M. Wizemann
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The committee reviewed epidemiologic evidence focusing on three outcomes: SIDS, all SUDI (sudden unexpected death in infancy), and neonatal death (infant death, whether sudden or not, during the first 4 weeks of life). Based on this review, the committee concluded that the evidence favors rejection of a causal relationship between some vaccines and SIDS; and that the evidence is inadequate to accept or reject a causal relationship between other vaccines and SIDS, SUDI, or neonatal death. The evidence regarding biological mechanisms is essentially theoretical, reflecting in large measure the lack of knowledge concerning the pathogenesis of SIDS.
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