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Hematopoietic Stem Cell Transplantation

By: Anthony D. Ho (Edited by) , Rainer Haas (Edited by) , Richard E. Champlin (Edited by)

Manufacture on Demand

Ksh 48,150.00

Format: Hardback or Cased Book

ISBN-10: 0824702735

ISBN-13: 9780824702731

Publisher: Taylor & Francis Inc

Imprint: CRC Press Inc

Country of Manufacture: US

Country of Publication: GB

Publication Date: Jul 25th, 2000

Publication Status: Active

Product extent: 620 Pages

Weight: 1212.00 grams

Product Classification / Subject(s): Clinical & internal medicine

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Integrates advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy. This book examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, infection, and more. It is for hematologists, oncologists, and others.
This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more.
Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life.
Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation
  • summarizes current understanding and development of clinical allogeneic HSC transplantation
  • discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation
  • considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors
  • details detection of bone marrow contamination by tumor cells and removal procedures
  • focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors
  • explores the effects of growth factor administration and leukapheresis on PB stem cell donors
  • shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use
  • reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells
  • employs automated fluorescence image cytometry to study early HSC behavior following seeding
    Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study,

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