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Glycolysis : Tissue-Specific Metabolic Regulation in Physio-pathological Conditions

By: Pedro Fontes Oliveira (Edited by) , Rita Ferreira (Edited by) , Rita Nogueira-Ferreira (Edited by)

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Ksh 32,050.00

Format: Paperback or Softback

ISBN-10: 0323917046

ISBN-13: 9780323917049

Publisher: Elsevier Science & Technology

Imprint: Academic Press Inc

Country of Manufacture: GB

Country of Publication: GB

Publication Date: Oct 18th, 2023

Publication Status: Active

Product extent: 490 Pages

Weight: 450.00 grams

Product Classification / Subject(s): Biophysics
Biochemistry
Carbohydrates

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Glycolysis: Tissue-Specific Metabolic Regulation in Physio-Pathological Conditions provides an integrated overview of glycolysis, spanning basic biochemistry, patho-physiology and therapeutic applications. The book also instructs in methods available to study the involvement of the glycolytic events in healthy biology and disease pathology. It begins with an overview of fundamental glycobiology followed by chapters dedicated to glycolysis physiology in organs and systems, pathologic conditions related to glycolytic alterations, glycolysis as a therapeutic target and in drug discovery efforts, and methodological approaches to advance new glycolysis research. Disease areas considered range from cancer to heart failure, diabetes, inborn glycolytic pathway defects, hematologic malignancies, osteoporosis, neurodegenerative diseases and viral Infections. Omics and computational modeling, interactive study methods, and glycolysis flux measurement are described in detail, with step-by-step descriptions of experimental protocols, set-up and analysis.

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