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By: Eric Ahrens (Edited by) , Ulrich Flogel (Edited by)
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Fluorine (19F) magnetic resonance imaging (MRI) has garnered significant interest owing to the properties of fluorinated materials and the 19F nucleus. Fluorinated materials can serve as therapeutic agents, drug-delivery vehicles, and imaging probes that rely on 19F MRI detection. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body, thus, no background signal. Fluorine-containing compounds are ideal tracer labels for many MRI applications. Moreover, the chemical shift and nuclear relaxation rate is responsive to physiology via creative molecular design.
Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design.
This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Flögel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics.
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